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Peganum Harmala (Syrian Rue) 10x Extract

Peganum harmala, also known as Syrian Rue, has very strong MAO-inhibiting properties. It can be used to make truffle trips stronger and make the trip last longer. This is a 10x extract, meaning one must be extra careful with dosage. Before ingestion, it's best to do some research in the links offered below.

Care must be taken with this product as MAO-inhibitors can be very dangerous when combined with the wrong food or drugs.

Contents: 1 gram of 10x Pegenum Harmala extract

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Contents: 1 gram of 10x Pegenum Harmala extract


Common use of Syrian rue has the effect of a psychopharmacological tool, making otherwise inactive plants active. Sometimes Syrian rue is used to strengthen and prolong the effects of substances that are active by themselves. Syrian rue prevents the breakdown of monoamine neurotransmitters by inhibiting the action of monoamine oxidase enzymes, a process known as MAO-inhibition. This renders substances like DMT and 5-MeO-DMT orally active and makes a psilocybin mushroom experience last longer and become stronger.

A small number of people is experimenting with the effects of only Syrian rue infusions or smoked seeds. The effects of low doses are sometimes referred to as 'the harmala buzz', as it tends to cause a buzzing feeling throughout the head and body. This is also the initial stage for most people taking a higher dose, though it generally unfolds into a stronger experience associated with nausea, stomach cramps and vomiting. Also, psychedelic effects, such as visual and auditive distortions and mystical phenomena, seem to be common for some people. The experience will last around 4 hours.


It is possible to consume the extract directly, by mixing it with water. For a Syrian rue only experience, doses are still experimental. To use this extract, people should start with 1:10 of a low dose, meaning they take 0.1 gram to see how they react. 0.5 grams is a high dose for most people.

For potentiating a normal or high dose of truffles, taking 0.3 grams of 10x extract 15 to 60 minutes prior to the truffles is an established method. Taking more usually results in more physical discomfort and no stronger effect. It will make the mushrooms 1½ to 2 times stronger. It also adds 1 to 3 hours to the duration.


The primary active ingredients in P. harmala are harmine and harmaline. (C. Raetsch 2005)


Warning: Peganum harmala contains strong MAO-inhibiting substances. This means it can be very dangerous when combined with certain foods or psychoactives. Even some that are totally harmless when taken by themselves.

Read more about which foods to avoid here:
Read more about MAO-i's here:

More Information
Strength 7
Duration 6 Hours
Quantity 1g
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